Recently I am researching about ANTIMICROBIAL ACTIVITY; EXPRESSION; COX-2; ANTIBACTERIAL; NANOPARTICLES; INHIBITION; ANTIFUNGAL; INFECTION; DELIVERY, Saw an article supported by the . Published in ELSEVIER in AMSTERDAM ,Authors: Mohamed, NA; Abd El-Ghany, NA; Abdel-Aziz, MM. The CAS is 119-61-9. Through research, I have a further understanding and discovery of Benzophenone. Quality Control of Benzophenone
Chitosan (Cs) was cross-linked with four various quantities of 4,4′-(5,5′-carbonylbis(1,3-dioxoisoindoline-5,2-diyl) )dibenzoyl isothiocyanate. Elemental analysis, FTIR and H-1 NMR spectroscopy assured that the amino groups of chitosan reacted with the isothiocyanate groups of the cross-linker producing four new hydrogels namely as BBTU-Cs-1, BBTU-Cs-2, BBTU-Cs-3, and BBTU-Cs-4 according to the increment of their cross-linking content, respectively. SEM showed their porous structures and XRD indicated their amorphous nature. Their swell ability increased with decreasing the medium pH value and with increasing cross-linking density. In comparison with the popular COX inhibitor Celecoxib, these hydrogels showed an inhibition activity towards COX enzymes with selective inhibition towards COX-2. Their inhibition activity could be arranged as follows: Celecoxib > BBTU-Cs-4 > BBTU-Cs-3 > BBTU-Cs-2 > BBTU-Cs-1. BBTU-CS-4 hydrogel exhibited a potent inhibition against COX-2 (IC50 0.42 mu g/ml) compared with that observed for the standard Celecoxib (IC50 026 mu g/ml). BBTIJ-Cs-4 is more potent against H. pylori compared to the other hydrogels. BBTU-Cs-4 at a concentration of 7.81 mu g/ml is able to kill 100% of the H. pylori and exhibits a preferential ability to inhibit 8935% of COX-2 than COX-1 (0%). These findings make BBTU-Cs-4 a promising anti-H. pylori and selective anti-inflammatory agent. (C) 2021 Elsevier B.V. All rights reserved.
Quality Control of Benzophenone. Bye, fridends, I hope you can learn more about C13H10O, If you have any questions, you can browse other blog as well. See you lster.
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem