Extracurricular laboratory: Synthetic route of 616-14-8

Here is just a brief introduction to this compound(616-14-8)Computed Properties of C5H11I, more information about the compound(1-Iodo-2-methylbutane) is in the article, you can click the link below.

Computed Properties of C5H11I. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 1-Iodo-2-methylbutane, is researched, Molecular C5H11I, CAS is 616-14-8, about Palladium-Catalyzed Arylation of Unactivated γ-Methylene C(sp3)-H and δ-C-H Bonds with an Oxazoline-Carboxylate Auxiliary. Author is Ling, Peng-Xiang; Fang, Sheng-Long; Yin, Xue-Song; Chen, Kai; Sun, Bo-Zheng; Shi, Bing-Feng.

A palladium-catalyzed arylation of unactivated γ-methylene C(sp3)-H and remote δ-C-H bonds by using an oxazoline-carboxylate directing group has been developed. Arylation occurs with a broad substrate scope and high tolerance of functional groups (i.e., halogen, nitro, cyano, ether, trifluoromethyl, amine, and ester). The oxazoline-type auxiliary can be removed under acidic conditions.

Here is just a brief introduction to this compound(616-14-8)Computed Properties of C5H11I, more information about the compound(1-Iodo-2-methylbutane) is in the article, you can click the link below.

Reference:
Thiomorpholine – Wikipedia,
Thiomorpholine | C4H9NS – PubChem