The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: (R)-(9H-Fluoren-9-yl)methyl (1-chloro-4-methyl-1-oxopentan-2-yl)carbamate( cas:198544-60-4 ) is researched.Formula: C21H22ClNO3.Trabocchi, Andrea; Stefanini, Irene; Morvillo, Manfredi; Ciofi, Leonardo; Cavalieri, Duccio; Guarna, Antonio published the article 《Chemical genetics approach to identify new small molecule modulators of cell growth by phenotypic screening of Saccharomyces cerevisiae strains with a library of morpholine-derived compounds》 about this compound( cas:198544-60-4 ) in Organic & Biomolecular Chemistry. Keywords: oxazolopyrazine pyrazinooxazine morpholine preparation Saccharomyces cerevisiae cell growth modulator. Let’s learn more about this compound (cas:198544-60-4).
A chem. genetics approach has been applied in the screening of yeast deletants strains with a pool of morpholine-derived compounds in order to identify candidate small mols. able to produce phenotypic effects on yeast cells. The anal. of the effects of structurally diverse mols. towards cell growth rate in both exponential and stationary phases provides a tool to select candidate compounds for subsequent assays to identify new chem. entities as chem. probes for drug discovery.
Different reactions of this compound((R)-(9H-Fluoren-9-yl)methyl (1-chloro-4-methyl-1-oxopentan-2-yl)carbamate)Formula: C21H22ClNO3 require different conditions, so the reaction conditions are very important.
Reference:
Thiomorpholine – Wikipedia,
Thiomorpholine | C4H9NS – PubChem