Final Thoughts on Chemistry for 3-Amino-2-(4-chlorophenyl)propane-1-sulfonic acid

If you are interested in 125464-42-8, you can contact me at any time and look forward to more communication. Name: 3-Amino-2-(4-chlorophenyl)propane-1-sulfonic acid.

In an article, author is Lanoix, J. -P., once mentioned the application of 125464-42-8, Name: 3-Amino-2-(4-chlorophenyl)propane-1-sulfonic acid, Name is 3-Amino-2-(4-chlorophenyl)propane-1-sulfonic acid, molecular formula is C9H12ClNO3S, molecular weight is 249.7145, MDL number is MFCD00216817, category is thiomorpholine. Now introduce a scientific discovery about this category.

SUTEZOLID Oxazolidinone Antibacterial Treatment of Tuberculosis

In the context of increasing drug resistance among Mycobacterium tuberculosis (Mtb) strains, new, potent and well tolerated drugs are urgently needed. Bedaquiline has obtained accelerated approval, but additional novel agents are needed to enable effective combination chemotherapy of extensively drug-resistant tuberculosis (TB). Linezolid, the first and only marketed oxazolidinone antibiotic, has shown certain activity against Mtb. However, serious safety concerns related to long-term administration have limited its utility for TB treatment. Sutezolid (formerly PNU-100480) is a thiomorpholine analogue of linezolid with greater potency in several experimental TB models and the potential for a superior safety profile. This article reviews available preclinical and clinical data regarding the pharmacokinetics, safety and efficacy of sutezolid and presents the case for its further development for the treatment of TB.

If you are interested in 125464-42-8, you can contact me at any time and look forward to more communication. Name: 3-Amino-2-(4-chlorophenyl)propane-1-sulfonic acid.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem